程家維
姓名 程家維
職稱 教授
聯絡電話 03-5742763
聯絡地址 生科二館424室
電子郵件 jwcheng@life.nthu.edu.tw
授課領域 生物分子結構、藥物設計
研究專長 生物分子結構、藥物設計
年度 論文名稱
2010 Yu, H.Y., Huang, K.C., Yip, B.S., Tu, C.H., Chen, H.L., Cheng, H.T. and Cheng, J.W., Rational design of tryptophan-rich antimicrobial peptides with enhanced antimicrobial activities and specificities, Chembiochem, 11, 16, pp2273-2282, (SCI)
2010 Chen, H.L., Her, S.Y. Huang, K.C., Cheng, H.T., Wu, C.W., Wu, S.C. and Cheng, J.W., Identification of a Heparin Binding Peptide From the Japanese Encephalitis Virus Envelope Protein, Biopolymers, 94, 3, pp331-338, (SCI)
2009 Yip, B.S., Chen, H.L., Cheng, H.T., Wu, J.M. and Cheng, J.W., Solution Structure and Model Membrane Interactions of P-113, a Clinically Active Antimicrobial Peptide Derived from Human Saliva, Journal of the Chinese Chemical Society, 56, 5, pp961-966, (SCI)
2009 Wu, J.M., Jan, P.S., Yu, H.C., Haung, H.Y., Fang, H.J., Chang, Y.I., Cheng, J.W. and Chen, H.M. , Structure and function of a custom anticancer peptide, CB1a, Peptides , 30, 5, pp839-848, (SCI)
2009 Wang, C.W., Yip, B.S., Cheng, H.T., Wang, A.H., Chen, H.L., Cheng, J.W. and Lo, H.J. , Increased potency of a novel D-beta-naphthylalanine-substituted antimicrobial peptide against fluconazole-resistant fungal pathogens, Fems Yeast Research , 9, 6, pp967-970, (SCI)
2008 Weng, K.Y., Chou, N.J. and Cheng, J.W. , Triggering vacuum capillaries for pneumatic pumping and metering liquids in point-of-care immunoassays, Lab on a Chip, 8, 7, pp1216-1219, (SCI)
2008 Huang, K.C., Lee, M.C., Wu, C.W., Huang, K.J., Lei, H.Y. and Cheng, J.W., Solution structure and neutralizing antibody binding studies of domain III of the dengue-2 virus envelope protein, Proteins-Structure Function and Bioinformatics, 70, 3, pp1116-1119, (SCI)
2008 Cheng, H.T., Huang, K.C., Yu, H.Y., Gao, K.J., Zhao, X.X., Li, F., Town, J., Gordon, J.R. and Cheng, J.W., A new protocol for high-yield purification of recombinant human CXCL8((3-72))K11R/G31P expressed in Escherichia coli, Protein Expression and Purification, 61, 1, pp65-72, (SCI)
2007 Wu, J.M., Wei, S.Y., Chen, H.L., Weng, K.Y., Cheng, H.T. and Cheng, J.W., Solution structure of a novel D-ss-naphthylalanine substituted peptide with potential antibacterial and antifungal activities, Biopolymers, 88, 5, pp738-745, (SCI)
2006 Huang, K.C., Cheng, H.T., Pai, M.T., Tzeng, S.R. and Cheng, J.W., Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase, Journal of Biomolecular NMR, 36, 1, pp73-78, (SCI)
2006 Wei, S.Y., Wu, J.M., Kuo, Y.Y., Chen, H.L., Yip, B.S., Tzeng, S.R. and Cheng, J.W. , Solution structure of a novel tryptophan-rich Peptide with bidirectional antimicrobial activity, Journal of Bacteriology , 188, 1, pp328-334, (SCI)
2005 Wu CW, Lin YT, Huang KC, Cheng JW. "1H, 15N and 13C resonance assignments of the domain III of the Dengue virus envelope protein." (2005) J Biomol NMR. 33,76.
2003 K.P. Wu, C.W. Wu, Y.P. Tsao, T.W. Kuo, Y.C. Lou,C.W. Lin, S.C. Wu and J.W. Cheng, " Structural basis of a flavivirus recognized by its neutralizing antibody: solution structure of the domain III of the Japanese encephalitis virus envelope protein " (2003) Journal of Biological Chemistry 278, 46007-46013.
2003 M.T. Pai, C.S. Yang, S.R. Tzeng, C. Wang and J.W. Cheng, " 1H, 15N and 13C resonance assignments of the tetratricopeptide repeat (TPR) domain of hSGT " (2003) Journal of Biomolecular NMR 26, 381-382.
2002 M.T. Pai, K.C. Huang, S.R. Tzeng, and J.W. Cheng, "1H, 15N and 13C resonance assignments of the SH2 domain of Bruton's tyrosine kinase" (2002) Journal of Biomolecular NMR 24, 163-164.
2002 F.D. Lung, J.Y. Tsai, S.Y. Wei, J.W. Cheng, C. Chen, P. Li, and P.P. Roller, "Novel peptide inhibitors for Grb2 SH2 domain and their detection by surface plasmon resonance" (2002) Journal of Peptide Research 60, 143-149.
2001 M.L. Jain, Y.P. Tsao, N.L. Ho, and J.W. Cheng, "A Facile Synthesis of [N1, NH2-15N2]Adenine, [N3, NH2-15N2]Adenine and [N1, N3, NH2-15N3]Adenine" (2001) Journal of Organic Chemistry 66, 6472-6475
2001 Y.P. Tsao, L.Y. Wang, S.T. Hsu, M.L. Jain, S.H. Chou, W.C. Huang, and J.W. Cheng, "The Solution Structure of [d(CGC)r(amamam)d(TTTGCG)]2" (2001) Journal of Biomolecular NMR 21, 209-220.
2000 S.R. Tzeng, M.T. Pai, F.T. Lung, C.W. Wu, P.P. Roller, B. Lei, C.J. Wei, S.C. Tu, S.H. Chen, W.J. Soong, and J.W. Cheng, "Stability and Peptide Binding Specificity of BTK SH2 Domain: Molecular Basis for X-Linked Agammaglobulinemia" (2000) Protein Science 9, 2377-2385.
2000 S.T. Hsu, M.T. Chou, and J.W. Cheng, "The Solution Structure of [d(CGC)r(aaa)d(TTTGCG)]2: Hybrid Junctions Flanked by DNA Duplexes" (2000) Nucleic Acids Research 28, 1322-1331.
2000 Y.C. Lou, I.J. Lin, M.T. Pai, and J.W. Cheng, "Solution Structure of an N-Capping Peptide from the N-terminal Leucine-Repeat Region of Hepatitis Delta Antigen" (2000) Archives of Biochemistry and Biophysics 377, 219-227.
2000 S.R. Tzeng, Y.C. Lou, M.T. Pai, and J.W. Cheng, "Solution Structure of the BTK SH3 Domain Complexed with a Proline-Rich Peptide from p120cbl" (2000) Journal of Biomolecular NMR 16, 303-312.
2000 S.T. Hsu, M.T. Chou, S.H. Chou, W.C. Huang, and J.W. Cheng, "Hydration of [d(CGC)r(aaa)d(TTTGCG)]2" (2000) Journal of Molecular Biology 295, 1129-1137.
1999 Y.C. Lou, F.T. Lung, M.T. Pai, S.R. Tzeng, P.P. Roller and J.W. Cheng, "Solution Structure and Dynamics of a Nonphosphorelated Cyclic Peptide Inhibitor for the Grb2 SH2 Domain" (1999) Archives of Biochemistry and Biophysics 372, 309-314.
1999 S.H. Chou, Y.Y. Tseng, Y.R. Chen, and J.W. Cheng, "Structural Studies of Symmetric DNA Undecamers Containing Non-Symmetrical Sheared (PuGAPu):(PyGAPy) Motifs" (1999) Journal of Biomolecular NMR 14, 157-167.
1999 I.J. Lin, Y.C. Lou, M.T. Pai, H.N. Wu and J.W. Cheng, "Solution Structure and RNA Binding Activity of the N-terminal Leucine-Repeat Region of Hepatitis Delta Antigen" (1999) PROTEINS: Structure, Function, and Genetics 37, 121-129.
1998 J.W. Cheng, I.J. Lin, Y.C. Lou, M.T. Pai, and H.N. Wu, "Local Helix Content and Nucleic Acid Binding Activity of the N-terminal Leucine-Repeat Region of Hepatitis Delta Antigen" (1998) Journal of Biomolecular NMR 12, 183-188.
1998 C.C. Cheng, Y.H. Jian, C.J. Lo, and J.W. Cheng, "Design and Characterization of a Short HMG-I/DAT1 Chimeric Peptide that Binds Specifically to the Minor Groove of DNA" (1998) Journal of the Chinese Chemical Society 45, 619-624.
1998 C.S. Lee, T.K.S. Kumar, J.W. Cheng, and C. Yu, "Main-Chain Dynamics of Cardiotoxin II from Taiwan Cobra (Naja naja atra) as Studied by Carbon-13 NMR at Natural Abundance - Delineation of the role of functionally important residues" (1998) Biochemistry 37, 155-164.
1997 H.V. Patel, S.R. Tzeng, C.Y. Liao, S.H. Chen, and J.W. Cheng, "SH3 Domain of Bruton's Tyrosine Kinase can Bind to Proline-Rich Peptides of TH Domain of the Kinase and p120cbl" (1997) PROTEINS: Structure, Function, and Genetics 29, 545-552.
1996 Y.J. Chen, S.C. Lin, S.R. Tzeng, H.V. Patel, P.C. Lyu, and J.W. Cheng, "Stability and Folding of the SH3 Domain of Bruton's Tyrosine Kinase" (1996) PROTEINS: Structure, Function, and Genetics 26, 465-471.
1996 S.H. Chou, L. Zhu, Z. Gao, J.W. Cheng, and B.R. Reid, "Hairpin Loops Consisting of Single Adenine Residues Closed by Sheared AA and GG Pairs Formed by the DNA Triplets AAA and GAG: Solution Structure of the d(GTACAAAGTAC) Hairpin" (1996) Journal of Molecular Biology 264, 981-1001.
1996 J.W. Cheng, C.C. Cheng, P.C. Lyu, S.T. Chen, and T.H. Lin, "Solution Conformation of a Peptide Corresponding to Residues 151-172 of HIV-1 Integrase using NMR and CD Spectroscopy" (1996) International Journal of Peptide & Protein Research 47, 117-122.
1995 J.W. Cheng, C. Chen, T.H. Huang, S.H. Chou, and S.H. Chen, "Conformation of the Propeptide Domain of Factor IX" (1995) Biochimica et Biophysica Acta 1245, 227-231.
1994 S.H. Chou, J.W. Cheng, O. Fedoroff, and B.R. Reid "DNA Sequence GCGAATGAGC Containing the Human Centromere Core Sequence GAAT Forms a Self-complementary Duplex with Sheared GA Pairs in Solution" (1994) Journal of Molecular Biology 241, 467-479.
1994 C.A. Lepre, D.A. Pearlman, J.W. Cheng, M.T. DeCenzo, D.J. Livingston, and J.M. Moore "Solution Structure of FK506 Bound to the R42K, H87V Double Mutant of FKBP-12" (1994) Biochemistry 33, 13571-13580.
1994 J.W. Cheng, C.A. Lepre, and J.M. Moore "15N NMR Relaxation Studies of the FK506 Binding Protein: Dynamic Effects of Ligand Binding and Implications of Calcineurin Recognition" (1994) Biochemistry 33, 4093-4100.
1993 J.W. Cheng, C.A. Lepre, S. Chambers, J. R. Fulghum, J. A. Thomson, J.M. Moore, "15N NMR Relaxation Studies of the FK506 Binding Protein: Backbone Dynamics of the Uncomplexed Receptor" (1993) Biochemistry 32, 9000-9010.
1993 C.A. Lepre, J.W. Cheng, J.M. Moore "Dynamics of a receptor-bound ligand by heteronuclear NMR: FK506 bound to FKBP-12" (1993) J. Am. Chem. Soc. 115, 4929-4930.
1992 S.H. Chou, J.W. Cheng, O. Fedoroff, V. Chuprina, and B.R. Reid, "Adjacent G:A Mismatch Base Pairs Contain BII Phosphodiesters in Solution." (1992) J. Am. Chem. Soc. 114, 3114-3115.
1992 J.W. Cheng, S.H. Chou, and B.R. Reid, "Base Pairing Geometry in GA Mismatches Depends Entirely on the Neighboring Sequence" (1992) Journal of Molecular Biology 228, 1037-1041.
1992 S.H. Chou, J.W. Cheng, and B.R. Reid, "The solution structure of [d(ATGTGCGAATA)]2: Adjacent GA Mismatches Stabilized By Cross-Strand Base-Stacking and BII phosphate Groups." (1992) Journal of Molecular Biology 228, 138-155.
1992 J.W. Cheng, S.H. Chou, M. Salazar, and B.R. Reid, "The solution structure of [d(GCGTATACGC)]2," (1992) Journal of Molecular Biology 228, 118-137.
1989 J.W. Cheng, and F.T. Luo, "Palladium-Catalyzed intramolecular arylpalladation via ultrasonics," Bull. Inst. Chem, Academia Sinica 36, 9-15 (1989).
1988 B. O'connor, Yantao Zhang, N. Eiichi, F.T. Luo, and J.W. Cheng, "Metal promoted cyclizations. 20. Palladium catalyzed cyclization of alkenyl and aryl halides containing a,b-unsaturated carbonyl groups via intramolecular carbopalladation," Tetrahedron Letters 29, 3903-3906 (1988).
1988 J.W. Cheng, and F.T. Luo, "Coupling of aryl grignard reagents by electron transfer to 2,3-dichloropropene," Tetrahedron Letters 29, 1293-1294 (1988).
國家 學校名稱 系所 學位
美國 西雅圖華盛頓大學 博士